Sepsis-associated acute kidney injury (SA-AKI) is one of the most severe and complex forms of kidney injury, significantly increasing morbidity and mortality. It results from a combination of systemic inflammation, hemodynamic instability, microvascular dysfunction, and direct cellular injury. At IMH, SA-AKI management is delivered through a tightly coordinated ICU-based care model involving nephrology, critical care, infectious disease, and emergency medicine teams.

Early recognition of sepsis and kidney involvement is critical. IMH protocols emphasize rapid identification through clinical signs, laboratory markers, and early warning systems. Once SA-AKI is suspected, immediate interventions are initiated to stabilize hemodynamics, control infection, and support organ function.

Management includes aggressive infection control with timely antibiotics, source control procedures, and hemodynamic optimization using fluids and vasopressors when necessary. Nephrologists assess kidney function trends, urine output, and metabolic status to guide renal support decisions.

Renal replacement therapy may be required in cases of severe metabolic derangement, fluid overload, or refractory acidosis. IMH offers both intermittent and continuous dialysis modalities in ICU settings, tailored to patient stability.

By combining rapid response, advanced critical care infrastructure, and nephrology expertise, IMH provides comprehensive management of sepsis-associated AKI, improving survival and recovery outcomes.