Rhabdomyolysis Management

Rhabdomyolysis is a serious medical condition caused by rapid breakdown of skeletal muscle fibers, leading to the release of intracellular contents such as myoglobin, potassium, and creatine kinase into the bloodstream. These substances can cause severe metabolic disturbances and acute kidney injury (AKI) if not promptly managed. At International Modern Hospital (IMH), rhabdomyolysis is treated as a nephrology and critical care emergency requiring early intervention and close monitoring.

Common causes of rhabdomyolysis include trauma, prolonged immobilization, extreme physical exertion, heat stroke, drug toxicity, alcohol abuse, infections, and metabolic disorders. In the UAE, cases are frequently associated with dehydration, heat exposure, and exertional injury.

Early recognition is critical. Patients may present with muscle pain, weakness, swelling, dark-colored urine, or reduced urine output. Laboratory findings typically show markedly elevated creatine kinase levels, electrolyte abnormalities, and rising serum creatinine.

IMH’s management protocol focuses on aggressive but carefully monitored fluid resuscitation to maintain kidney perfusion and dilute nephrotoxic myoglobin. Isotonic intravenous fluids are administered with close monitoring of urine output, electrolytes, and cardiovascular status. Nephrologists guide fluid strategies to prevent both kidney injury and fluid overload.

Electrolyte abnormalities, particularly hyperkalemia and hypocalcemia, are corrected promptly to prevent cardiac complications. Medications that may worsen kidney injury are discontinued. In severe cases, renal replacement therapy may be required for refractory metabolic disturbances or established AKI.

Through early diagnosis, structured protocols, and multidisciplinary care, IMH ensures optimal outcomes for patients with rhabdomyolysis while prioritizing kidney preservation and long-term recovery.

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